Lincomycin 500mg is an antibiotic that is made in the form of a hard gelatin capsule usually used to treat strong infections caused by sensitive bacteria. The main active ingredient contained in Lincomycin 500mg is lincosamides, which is a culture from streptomyces lincolnensis.
Properties of Lincomycin (500mg)
Microbiologically, depending on the sensitivity of microorganism and the concentration of the antibiotic, Lincomycin may be either Bactericidal or Bacteriostatic.
Lincomycin (500mg) oral dosage
After oral administration, the absorption is 20-30%. That is, after an oral dose of 500mg peak levels are 3g/ml and are reached within 2 to 4 hours. This value decreases if Lincomycin is taken with meal.
If the causative agent is Gram-positive organisms, serum levels are maintained above MIC between 1 and 2 mcg/ ml for 6- 8 hours.
Lincomycin injection
IM administration of a single dose of 600 mg produces a peak serum level of 12-20 micrograms/ml at half to one hour with detectable concentration as long as 24 hours.
The IV infusion over 2-hour intervals of 600 mg of Lincomycin resulted in a maximum serum concentration of 20 micrograms/ml at 30 minutes yielding a concentration of 1-2 micrograms/ ml at 14 hours.
What is the dosage of Lincomycin
Lincomycin (500mg) is normally taken with water orally and is taken 1 hour before or after meals. Always tell your patients to use water to take the drug.
The dose of Lincomycin for adults is always 500mg to which the adults take the capsule daily 3 to 4 times.
For your patients who are children, and must be from 1 month old, the dose of Lincomycin for them is from 30 to 60mg/kg/day and the Lincomycin syrup can be orally administered to them.
What is the side effects of Lincomycin?
Every drug has side effects, that’s why you should be careful when administering drugs to your patients. Reactions like gastrointestinal glossitis, stomatitis, nausea, vomiting, antibiotic-associated diarrhea, and colitis have been said to be the side effects of Lincomycin. If your patient is allergic to Lincomycin, kindly discontinue the drugs upon your discovery.
What is Lincomycin used for?
Lincomycin is used to treat infections caused by susceptible strains of Gram-positive anaerobes Staphylococcus, Streptococcus, Pneumonia, Septicaemia, Endocarditis, abscess, peritonitis, pelvic infections, bone and joint infections, URTI, LRTI, and Bacillary dysentery
Is Lincomycin safe in pregnancy?
There are limited data on the use of lincomycin in pregnancy. Although, almost all antibiotics have significant medical effects on pregnant women. Strictly, it should not be given to a pregnant woman who is hypersensitive to Lincomycin.
Can a breastfeeding mother take Lincomycin?
Unlike some other antibiotics, there are no adequate reports or studies on the effects of Lincomycin on nursing mothers. Lincomycin is excreted into human breast milk, achieving concentrations of 0.5-2.4mcg/ml. Even if the mother breastfeeds the newborn, out of the 100% absorption, the daily dose would be <2mg.
Brands of Lincomycin in the market
There are many brands of Lincomycin in the market ranging from different companies such as Greenlife Pharm., Embassy Pharm., Maydon Pharm., Derms Pharm., Geneith Pharm., etc. All Lincomycin are the same because they are composed of the same active ingredients of lincosamide, unless in the case where the company comprises in the right percentage of it.
Lincomycin price in Nigeria
Lincomycin of different companies sell at almost the same price, unless the company whose Lincomycin is more popular than the others. The current price of Lincomycin is about #7000 to #8000 per roll of 10 packets. Each card is around #250 to #300.
